Nature Custom Media / Elie Diner

Nature • 3rd July 2025

Precision proteomics demands precision antibodies

Despite the hundreds of millions of vials of blood drawn every year for medical testing, scientists have only scratched the surface of its diagnostic potential. The blood proteome — which includes all proteins secreted into the blood — is a vast and largely untapped resource for markers of health or disease. One key analytical challenge is the need to simultaneously detect multiple protein biomarkers in the blood with high sensitivity. Tod White, chief business officer at proteomics company Alam...

Flow, not flaws, for human immune monitoring studies

Much of what biologists know about the human immune system has been — quite literally — illuminated by flow cytometry. For more than 70 years, this technology has evolved to become one of immunology’s most powerful techniques; able to rapidly detect 30 distinct cellular characteristics at once, across millions of cells.1 The snapshot produced by flow cytometry provides a glimpse into the rarest populations of immune cells and their impact on health and disease.To closely monitor immune system ch...